The role of L-arginine in the treatment of cardiovascular diseases: the focus is on the choice of effective dose

Author: O.V. Kuryata, M.M. Grechanyk
Department of Internal Medicine 2 State Institution «Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine»
Published: Medical Newspaper «Health of Ukraine» № 11 (456), June 2019

The role of L-arginine in the treatment of cardiovascular diseases: the focus is on the choice of effective dose

L-arginine is a conditionally essential amino acid that was first isolated in 1886 by E. Schulze and E. Steiger, and its structure was established by E. Schulze and E. Winterstei in 1897 [1]. L-arginine is used several times ways for the synthesis of protein and low molecular weight bioactive substances (eg, nitric oxide - NO, ornithine, proline, creatine and polyamines), which are of great physiological importance. In addition, arginine regulates cell signaling pathways and gene expression to improve cardiovascular function, increase insulin sensitivity [2], increasing muscle mass and reducing obesity in humans.
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